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Hydromorphone and daridorexant each improve sedation. Modify Therapy/Monitor Closely. Coadministration raises possibility of CNS melancholy, which can lead to additive impairment of psychomotor effectiveness and induce daytime impairment. Adrenal insufficiency: Circumstances of adrenal insufficiency are reported with opioid use, far more normally pursuing increased than 1 month of use... https://angelinav726cqc6.empirewiki.com/user

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