Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors in the central nervous system, conolidine modulates alternate molecular targets. A Science Advances study found that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. By influencing https://alternative-natural-pain93444.verybigblog.com/36651935/helping-the-others-realize-the-advantages-of-alternative-natural-pain-relief-to-replace-traditional-painkillers